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Article

The rough colony morphotype of Mycobacterium avium exhibits high virulence in human macrophages and mice.

Journal of medical microbiology - 1 Jul 2020

Nishimura Tomoyasu, Shimoda Masayuki, Tamizu Eiko, Uno Shunsuke, Uwamino Yoshifumi, Kashimura Shoko, Yano Ikuya, Hasegawa Naoki

Abstract excerpt

Introduction. The incidence of Mycobacterium avium complex (MAC) pulmonary disease (MAC PD), a refractory chronic respiratory tract infection, is increasing worldwide. MAC has three predominant colony morphotypes: smooth opaque (SmO), smooth transparent (SmT) and rough (Rg).Aim. To determine whether colony morphotypes can predict the prognosis of MAC PD, we evaluated the virulence of SmO, SmT and Rg in mice and...

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Identifiers

PMID: 32589124
DOI: 10.1099/jmm.0.001224

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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