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Article

Association of physical activity and polymorphisms in FGFR2 and DNA methylation related genes with breast cancer risk.

Cancer epidemiology - 1 Dec 2014

Xi Jing, Su Yi, Beeghly Fadiel Alicia, Lin Ying, Su Feng-Xi, Jia Wei-Hua, Tang Lu-Ying, Ren Ze-Fang

Abstract excerpt

PURPOSE: Physical activity, a protective factor for breast cancer, increases the level of DNA methylation. Fibroblast growth factor receptor 2 (FGFR2), a confirmed breast cancer susceptibility gene, is predisposed to be methylated. Therefore, DNA methylation related genes, such as methylenetetrahydrofolate reductase (MTHFR), methionine synthase (MTR), and DNA methyltransferase (DNMT), together with physical...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Genetic

Share to Polymorphism, Single Nucleotide

Share to Receptor, Fibroblast Growth Factor, Type 2

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Source

Identifiers

PMID: 25270516
DOI: 10.1016/j.canep.2014.09.002

Genes

FGFR2
MET
MTHFR
MTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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