Article
The role of FGF-2/HGF and fibronectin matrix on pleomorphic adenoma myoepithelial cell morphology and immunophenotype: an in vitro study.
Growth factors (Chur, Switzerland) - 1 Feb 2015
Silva Carolina Amália Barcellos, Nardello Laura Cristina Leite, Garcia Frederico Windlin, Araújo Ney Soares de, Montalli Victor Angelo, Araújo Vera Cavalcanti de, Martinez Elizabeth Ferreira
Abstract excerpt
Myoepithelial cells play a central role in glandular tumors, regulating the progression of in situ to invasive neoplasias, with the tumor microenvironment being shown to be involved in both initiation and progression. This study aimed to analyze the in vitro effects of fibroblast growth factor-2 (FGF-2) and hepatocyte growth factor (HGF) in myoepithelial cells under the influence of the fibronectin matrix...
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