Article
Identification of Proteins Involved in Human Sperm Motility Using High-Throughput Differential Proteomics
24 Sept 2014
Abstract excerpt
Mammalian sperm motility is a prerequisite for in vivo fertilization, and alterations in this parameter are commonly observed in infertile males. However, we still do not have a complete understanding of the molecular mechanisms controlling it. The aim of this study was to identify proteins involved in human sperm motility deficiency by using TMT protein labeling and LC-MS/MS. Two complementary approaches were...
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