Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The correlation of α-globin gene mutations and the XmnI polymorphism with clinical severity of Hb E/β-thalassemia.

Hemoglobin - 1 Jan 2014

Charoenkwan Pimlak, Teerachaimahit Pimjan, Sanguansermsri Torpong

Abstract excerpt

Clinical severity assessment and molecular analysis of β-, α-globin genes and the -158 (C > T) XmnI polymorphism of the (G)γ-globin gene were performed in 80 pediatric patients with Hb E (HBB: c.79G > A)/β-thalassemia (β-thal) to investigate the effects of coinheritance of α-thalassemia (α-thal)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to alpha-Globins
Share to alpha-Thalassemia
Share to beta-Thalassemia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Deoxyribonucleases, Type II Site-Specific

Share to gamma-Globins

Share to Hemoglobin E

Share to Thailand

Source

Identifiers

PMID: 25238043
DOI: 10.3109/03630269.2014.952744

Genes

HBB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25238043-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The correlation of α-globin gene mutations and the XmnI polymorphism with clinical severity of Hb E/β-thalassemia.PMID 25238043Read ↗

Genetic factors affecting clinical severity in beta-thalassemia syndromes.Semantic proximity Read ↗

Xmn1-G γ polymorphism and clinical predictors of severity of disease in β-thalassemia intermedia.Semantic proximity Read ↗

Modifying effect of XmnI, BCL11A, and HBS1L-MYB on clinical appearances: A study on β-thalassemia and hemoglobin E/β-thalassemia patients in Indonesia.Semantic proximity Read ↗

Variable severity of beta-thalassemia patients of eastern India: effect of alpha-thalassemia and xmnI polymorphism.Semantic proximity Read ↗

XmnI POLYMORPHISM AND DISEASE SEVERITY IN PATIENTS WITH BETA THALASSEMIA FROM NORTHERN PAKISTAN.Semantic proximity Read ↗

Beta-globin gene cluster polymorphisms are strongly associated with severity of HbE/beta(0)-thalassemia.Semantic proximity Read ↗

Association between Different Polymorphic Markers and β-Thalassemia Intermedia in Central Iran.Semantic proximity Read ↗

Molecular Understanding of Non-Transfusion-Dependent Thalassemia Associated with Hemoglobin E-β-Thalassemia in Northeast Thailand.Semantic proximity Read ↗

Hb E-β-Thalassemia in Five Indian States.Semantic proximity Read ↗

Molecular understanding of unusual HbE-β+-thalassemia with Hb phenotype similar to HbE heterozygote: simple and rapid differentiation using HbE levels.Semantic proximity Read ↗

Genetic Mutation of Hb E/beta Thalassemia Patient in Bangladesh and Its Relation With Clinical SeveritySemantic proximity Read ↗

Effect of deletions in the α-globin gene on the phenotype severity of β-thalassemia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.