Article
Mitochondrial dysfunction and bipolar disorder.
Current topics in behavioral neurosciences - 1 Jan 2000
Kato Tadafumi
Abstract excerpt
The mitochondrial dysfunction hypothesis was proposed to integrate various findings in bipolar disorder (BPD). This hypothesis is supported by possible roles of maternal inheritance, comorbidity with mitochondrial diseases, the mechanism of action of mood stabilizers, magnetic resonance spectroscopy, mitochondrial DNA mutations, gene expression analysis, and phenotypes of animal models. Mitochondrial dysfunction...
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