Article
Comparison of LAIR-1 genetic pathways in murine vs human internal organs.
Gene - 15 Nov 2014
Sun Shuqiu, Jiao Yan, Wei Wei, Postlethwaite Arnold E, Gu Weikuan, Sun Dianjun
Abstract excerpt
Growing evidence suggests that defective expression or dysfunction of LAIR-1, a novel immunoinhibitory receptor for collagen, is closely associated with some autoimmune diseases, cancers, as well as viral infections. We analyzed the variation of LAIR-1 genetic pathways in murine versus human internal organs, including the lung and brain. The results showed that, under physiological conditions, LAIR-1 links more...
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