Article
Identification of Indian sub-continent as hotspot for HCV genotype 3a origin by Bayesian evolutionary reconstruction.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Dec 2014
Choudhary Manish Chandra, Natarajan Vidhya, Pandey Priyanka, Gupta Ekta, Sharma Shvetank, Tripathi Rachana, Kumar M Shesheer, Kazim Syed N, Sarin Shiv K
Abstract excerpt
BACKGROUND: Recent emphasis in Hepatitis C virus (HCV) evolutionary biology has focused on analysis using Core, E1/E2 and/or NS5b regions, with limited appreciation of full length genome. While HCV genotypes have been described as endemic in the Indian subcontinent, there has been no confirmation at the molecular evolutionary level of these genotypes. We have attempted here to determine the status of Indian HCV...
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