Article
Optimizing triple therapy and IFN/RBV-free regimens for hepatitis C virus infection.
Expert review of gastroenterology & hepatology - 1 Jan 2015
Chayama Kazuaki, Mitsui Fukiko, Hayes C Nelson
Abstract excerpt
Treatment of chronic hepatitis C virus infection has substantially improved following the advent of direct acting antiviral (DAA) agents. Although the first generation protease inhibitors telaprevir and boceprevir improved sustained viral response (SVR) rates, adverse events remain severe and immature termination of the therapy is frequent; however, intensive dose modification has improved completion and SVR...
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