Article
Direct-acting antivirals: the endgame for hepatitis C?
Current opinion in virology - 1 Jun 2017
D'Ambrosio Roberta, Degasperi Elisabetta, Colombo Massimo, Aghemo Alessio
Abstract excerpt
Directly-acting antivirals (DAA) have finally allowed all patients to be potentially cured from chronic hepatitis C (HCV) infection. All-oral, Interferon (IFN)-free regimens are based upon the combination of molecules targeting different sites of the HCV replication process. Three classes of DAA exist: protease inhibitors (anti-NS3/4A), RNA-dependent polymerase inhibitors (anti-NS5B) and anti-NS5A inhibitors,...
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