Article
Decade of optimizing therapy with direct-acting antiviral drugs and the changing profile of patients with chronic hepatitis C.
World journal of gastroenterology - 14 Feb 2023
Brzdęk Michał, Zarębska-Michaluk Dorota, Invernizzi Federica, Cilla Marta, Dobrowolska Krystyna, Flisiak Robert
Abstract excerpt
Chronic infection with the hepatitis C virus (HCV) remains a major health problem affecting approximately 58 million people worldwide. In the era of interferon (IFN)-based regimens, patients particularly infected with genotypes 1 and 4 achieved a low response rate. The implementation of direct-acting antivirals changed the landscape of HCV treatment. The increase in effectiveness provided us with the hope of...
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