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Downregulation and mutation of a Cadherin gene associated with Cry1Ac resistance in the Asian Corn Borer, Ostrinia furnacalis (Guenée).

Toxins - 11 Sept 2014

Jin Tingting, Chang Xue, Gatehouse Angharad M R, Wang Zhenying, Edwards Martin G, He Kanglai

Abstract excerpt

Development of resistance in target pests is a major threat to long-term use of transgenic crops expressing Bacillus thuringiensis (Bt) Cry toxins. To manage and/or delay the evolution of resistance in target insects through the implementation of effective strategies, it is essential to understand the basis of resistance. One of the most important mechanisms of insect resistance to Bt crops is the alteration of...

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PMID: 25216082
DOI: 10.3390/toxins6092676
PMCID: PMC4179154

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