Article
Variability in the cadherin gene in an Ostrinia nubilalis strain selected for Cry1Ab resistance.
Insect biochemistry and molecular biology - 1 Mar 2009
Bel Yolanda, Siqueira Herbert A A, Siegfried Blair D, Ferré Juan, Escriche Baltasar
Abstract excerpt
Transgenic corn expressing Cry1Ab (a Bacillus thuringiensis toxin) is highly effective in the control of Ostrinia nubilalis. For its toxic action, Cry1Ab has to bind to specific insect midgut proteins. To date, in three Lepidoptera species resistance to a Cry1A toxin has been conferred by mutations in cadherin, a protein of the Lepidoptera midgut membrane. The implication of cadherin in the resistance of an...
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