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Article

Beclin‐1–p53 interaction is crucial for cell fate determination in embryonal carcinoma cells

11 Sept 2014

Abstract excerpt

Emerging interest on the interrelationship between the apoptotic and autophagy pathways in the context of cancer chemotherapy is providing exciting discoveries. Complexes formed between molecules from both pathways present potential targets for chemotherapeutics design as disruption of such complexes could alter cell survival. This study demonstrates an important role of Beclin-1 and p53 interaction in cell fate...

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PMID: 25208472
DOI: 10.1111/jcmm.12386

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