Article
Molecular and prognostic correlates of cytogenetic abnormalities in chronic myelomonocytic leukemia: a Mayo Clinic-French Consortium Study.
American journal of hematology - 1 Dec 2014
Wassie Emnet A, Itzykson Raphael, Lasho Terra L, Kosmider Olivier, Finke Christy M, Hanson Curtis A, Ketterling Rhett P, Solary Eric, Tefferi Ayalew, Patnaik Mrinal M
Abstract excerpt
Four hundred and nine patients with chronic myelomonocytic leukemia (CMML) were included in the international collaborative study (268 (66%) and 141 (34%) from Mayo clinic and French consortium respectively). Thirty percent displayed an abnormal karyotype, including; 72% sole, 16% two, and 11% complex abnormalities. The most common abnormalities included; +8 (23%), -Y (20%), -7/7q-(14%), 20q- (8%), +21 (8%), and...
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