Article
Intrinsic mechanisms underlying the neurotrophic activity of adipose derived stem cells.
Experimental cell research - 1 Feb 2015
Tse Kai-Hei, Novikov Lev N, Wiberg Mikael, Kingham Paul J
Abstract excerpt
Adipose derived stem cells (ADSC) can be differentiated into Schwann cell-like cells which enhance nerve function and regeneration. However, the signalling mechanisms underlying the neurotrophic potential of ADSC remain largely unknown. In this study, we hypothesised that ADSC, upon stimulation with a combination of growth factors, could rapidly produce brain derived neurotrophic factor (BDNF) with a similar...
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