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Article

Cholinergic and dopaminergic neuronal differentiation of human adipose tissue derived mesenchymal stem cells.

Journal of cellular physiology - 1 Feb 2018

Marei Hany El Sayed, El-Gamal Aya, Althani Asma, Afifi Nahla, Abd-Elmaksoud Ahmed, Farag Amany, Cenciarelli Carlo, Thomas Caceci, Anwarul Hasan

Abstract excerpt

Mesenchymal stem cells (MSCs) are multipotent cells that can differentiate into various cell types such as cartilage, bone, and fat cells. Recent studies have shown that induction of MSCs in vitro by growth factors including epidermal growth factor (EGF) and fibroblast growth factor (FGF2) causes them to differentiate into neural like cells. These cultures also express ChAT, a cholinergic marker; and TH, a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28369825
DOI: 10.1002/jcp.25937

Genes

EGF
FGF2
MAP2
TUBB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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