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Article

Expression of a mitochondrial progesterone receptor in human spermatozoa correlates with a progestin‐dependent increase in mitochondrial membrane potential

3 Sept 2014

Abstract excerpt

The hyperactivation of human spermatozoa necessary for fertilization requires a substantial increase in cellular energy production. The factors responsible for increasing cellular energy remain poorly defined. This article proposes a role for a novel mitochondrial progesterone receptor (PR-M) in modulation of mitochondrial activity. Basic science studies demonstrate a 38 kDa protein with western blot analysis,...

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Identifiers

PMID: 25187426
DOI: 10.1111/j.2047-2927.2014.00263.x

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