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Article

Pharmacological treatment of chronic obstructive pulmonary disease: from evidence-based medicine to phenotyping.

Drug discovery today - 1 Dec 2014

Montuschi Paolo, Malerba Mario, Santini Giuseppe, Miravitlles Marc

Abstract excerpt

Chronic obstructive pulmonary disease (COPD) is characterized by large phenotype variability, reflected by a highly variable response to pharmacological treatment. Nevertheless, current guidelines suggest that patients with COPD of similar severity should be treated in the same way. The phenotype-based pharmacotherapeutic approach proposes bronchodilators alone in the nonfrequent exacerbator phenotype and a...

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PMID: 25182512
DOI: 10.1016/j.drudis.2014.08.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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