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Targeting forkhead box transcription factors FOXM1 and FOXO in leukemia (Review)

23 Jul 2014

Abstract excerpt

Deregulation of forkhead box (FOX) proteins has been found in many genetic diseases and malignancies including leukemia. Leukemia is a common neoplastic disease of the blood or bone marrow characterized by the presence of immature leukocytes and is one of the leading causes of death due to cancer. Forkhead transcription factors, FOXM1 and FOXO family members (FOXOs), are important mediators in leukemia...

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Identifiers

PMID: 25175498
DOI: 10.3892/or.2014.3357

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