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Genetic analysis of matrin 3 gene in French amyotrophic lateral sclerosis patients and frontotemporal lobar degeneration with amyotrophic lateral sclerosis patients.

Neurobiology of aging - 1 Dec 2014

Millecamps Stéphanie, De Septenville Anne, Teyssou Elisa, Daniau Mailys, Camuzat Agnès, Albert Mélanie, LeGuern Eric, Galimberti Daniela, Brice Alexis, Marie Yannick, Le Ber Isabelle

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) are adult-onset neurodegenerative diseases with overlapping clinical characteristics. They share common genetic causes and pathologic hallmarks such as TDP-43 neuronal accumulations. Recently, exome analysis identified mutations in matrin 3 (MATR3) gene in patients with familial ALS, suggesting a role for this gene in the...

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PMID: 25158920
DOI: 10.1016/j.neurobiolaging.2014.07.016

Genes

MATR3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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