Article
Clinical and genetic features of acute encephalopathy in children taking theophylline.
Brain & development - 1 May 2015
Saitoh Makiko, Shinohara Mayu, Ishii Atsushi, Ihara Yukiko, Hirose Shinichi, Shiomi Masashi, Kawawaki Hisashi, Kubota Masaya, Yamagata Takanori, Miyamoto Akie, Yamanaka Gaku, Amemiya Kaoru, Kikuchi Kenjiro, Kamei Atsushi, Akasaka Manami, Anzai Yuki, Mizuguchi Masashi
Abstract excerpt
BACKGROUND: Theophylline has recently been suspected as a risk factor of acute encephalopathy with biphasic seizures and late reduced diffusion (AESD), although there has been no systematic study on the relationship between acute encephalopathy in children taking theophylline (AET) and AESD. METHODS: We recruited 16 Japanese patients (11 male and 5 female, median age of 2 years and 7 months) with AET from 2008 to...
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