Effects of TSP-1-696 C/T polymorphism on bladder cancer susceptibility and clinicopathologic features.

doi:10.1016/j.cancergen.2014.06.023

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Article

Effects of TSP-1-696 C/T polymorphism on bladder cancer susceptibility and clinicopathologic features.

Cancer genetics - 1 Jun 2014

Gu Jinbao, Tao Jun, Yang Xiao, Li Pengchao, Yang Xuejian, Qin Chao, Cao Qiang, Cai Hongzhou, Zhang Zhengdong, Wang Meilin, Gu Min, Lu Qiang, Yin Changjun

Abstract excerpt

Thrombospondin-1 (TSP-1) is a glycoprotein that plays a major role in bladder cancer. We investigated the relationship between the distribution of the TSP-1 -696 C/T polymorphism (rs2664139) and the clinical features of bladder cancer. TaqMan assay was used to determine the genotype among the 609 cases and 670 controls in a Chinese population. Logistic regression was used to assess the association between the...

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PMID: 25150583
DOI: 10.1016/j.cancergen.2014.06.023

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