Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gestational Loss and Growth Restriction by Angiogenic Defects in Placental Growth Factor Transgenic Mice

22 Aug 2014

Abstract excerpt

OBJECTIVE: Angiogenesis is an important biological process during development, reproduction, and in immune responses. Placental growth factor (PlGF) is a member of vascular endothelial growth factor that is critical for angiogenesis and vasculogenesis. We generated transgenic mice overexpressing PlGF in specifically T cells using the human CD2-promoter to investigate the effects of PlGF overexpression. APPROACH...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Angiogenesis and VEGF in Cancer
Share to Pregnancy and preeclampsia studies
Share to Reproductive System and Pregnancy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25147341
DOI: 10.1161/atvbaha.114.303693

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gestational Loss and Growth Restriction by Angiogenic Defects in Placental Growth Factor Transgenic MicePMID 25147341Read ↗

Overexpression of Human sFLT1 in the Spongiotrophoblast Is Sufficient to Induce Placental Dysfunction and Fetal Growth Restriction in Transgenic MiceSemantic proximity Read ↗

Mechanistic insights into the development of severe fetal growth restrictionSemantic proximity Read ↗

PLGF, a placental marker of fetal brain defects after in utero alcohol exposureSemantic proximity Read ↗

Role of placenta growth factor in cancer and inflammationSemantic proximity Read ↗

Human sFLT1 Leads to Severe Changes in Placental Differentiation and Vascularization in a Transgenic hsFLT1/rtTA FGR Mouse ModelSemantic proximity Read ↗

The discovery of placenta growth factor and its biological activitySemantic proximity Read ↗

Mice overexpressing placenta growth factor exhibit increased vascularization and vessel permeabilitySemantic proximity Read ↗

Full Functional Knockout of Placental Growth Factor by Knockin with an Inactive Variant Able to Heterodimerize with VEGF-ASemantic proximity Read ↗

Placental‐Specific Overexpression of sFlt‐1 Alters Trophoblast Differentiation and Nutrient Transporter Expression in an IUGR Mouse ModelSemantic proximity Read ↗

Angiogenesis during primate placentation in health and diseaseSemantic proximity Read ↗

Placental Gene Therapy for Fetal Growth Restriction and Preeclampsia: Preclinical Studies and Prospects for Clinical ApplicationSemantic proximity Read ↗

Formyl peptide receptor-2 is decreased in foetal growth restriction and contributes to placental dysfunctionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.