Article
Molecular subtyping of bladder cancer using Kohonen self-organizing maps.
Cancer medicine - 1 Oct 2014
Borkowska Edyta M, Kruk Andrzej, Jedrzejczyk Adam, Rozniecki Marek, Jablonowski Zbigniew, Traczyk Magdalena, Constantinou Maria, Banaszkiewicz Monika, Pietrusinski Michal, Sosnowski Marek, Hamdy Freddie C, Peter Stefan, Catto James W F, Kaluzewski Bogdan
Abstract excerpt
Kohonen self-organizing maps (SOMs) are unsupervised Artificial Neural Networks (ANNs) that are good for low-density data visualization. They easily deal with complex and nonlinear relationships between variables. We evaluated molecular events that characterize high- and low-grade BC pathways in the tumors from 104 patients. We compared the ability of statistical clustering with a SOM to stratify tumors according...
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