Article
UBC13, an E2 enzyme for Lys63-linked ubiquitination, functions in root development by affecting auxin signaling and Aux/IAA protein stability.
The Plant journal : for cell and molecular biology - 1 Nov 2014
Wen Rui, Wang Sheng, Xiang Daoquan, Venglat Prakash, Shi Xianzong, Zang Yuepeng, Datla Raju, Xiao Wei, Wang Hong
Abstract excerpt
Unlike conventional lysine (K) 48-linked polyubiquitination, K63-linked polyubiquitination plays signaling roles in yeast and animals. Thus far, UBC13 is the only known ubiquitin-conjugating enzyme (E2) specialized in K63-linked polyubiquitination. Previous identification of Arabidopsis genes encoding UBC13 as well as its interacting partner UEV1 indicates that the UBC13-mediated ubiquitination pathway is...
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