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Article

Molecular Basis of Giant Cells in Tuberous Sclerosis Complex

20 Aug 2014

Abstract excerpt

The clinical observation of giant-cell brain tumors in a 15-year-old girl with epilepsy (the first patient noted to have tuberous sclerosis) has led to elucidation of the mTOR pathway, a critical regulator of cell size and growth.

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Identifiers

PMID: 25140966
DOI: 10.1056/nejmcibr1406613

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