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Article

Heavy metals, organic solvents, and multiple sclerosis: An exploratory look at gene-environment interactions.

Archives of environmental & occupational health - 1 Jan 2016

Napier Melanie D, Poole Charles, Satten Glen A, Ashley-Koch Allison, Marrie Ruth Ann, Williamson Dhelia M

Abstract excerpt

Exposure to heavy metals and organic solvents are potential etiologic factors for multiple sclerosis (MS), but their interaction with MS-associated genes is under-studied. The authors explored the relationship between environmental exposure to lead, mercury, and solvents and 58 single-nucleotide polymorphisms (SNPs) in MS-associated genes. Data from a population-based case-control study of 217 prevalent MS cases...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25137520
DOI: 10.1080/19338244.2014.937381
PMCID: PMC4334728

Genes

TNF
APOE
MBP
VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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