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Article

Characterizing genetic variation of adrenergic signalling pathways in Takotsubo (stress) cardiomyopathy exomes.

European journal of heart failure - 1 Sept 2014

Goodloe Adele H, Evans Jared M, Middha Sumit, Prasad Abhiram, Olson Timothy M

Abstract excerpt

AIMS: Exome sequencing was used to genotype comprehensively a Takotsubo (stress) cardiomyopathy (TC) cohort, enabling investigation of a vast 486 gene network for adrenergic signalling. METHODS AND RESULTS: Twenty-eight TC subjects, including a mother-daughter pair and five recurrent cases, underwent whole-exome sequencing. Frequencies of 17 common, functional adrenergic polymorphisms were statistically similar...

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Source

Identifiers

PMID: 25132214
DOI: 10.1002/ejhf.145

Genes

ADH5
CACNG1
EPHA4
PRKCA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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