Article
The strong selective sweep candidate gene ADRA2C does not explain domestication related changes in the stress response of chickens.
PloS one - 1 Jan 2014
Elfwing Magnus, Fallahshahroudi Amir, Lindgren Isa, Jensen Per, Altimiras Jordi
Abstract excerpt
Analysis of selective sweeps to pinpoint causative genomic regions involved in chicken domestication has revealed a strong selective sweep on chromosome 4 in layer chickens. The autoregulatory α-adrenergic receptor 2C (ADRA2C) gene is the closest to the selective sweep and was proposed as an important gene in the domestication of layer chickens. The ADRA2C promoter region was also hypermethylated in comparison to...
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