Article
Genetics of epilepsy: The testimony of twins in the molecular era.
Neurology - 16 Sept 2014
Vadlamudi Lata, Milne Roger L, Lawrence Kate, Heron Sarah E, Eckhaus Jazmin, Keay Deborah, Connellan Mary, Torn-Broers Yvonne, Howell R Anne, Mulley John C, Scheffer Ingrid E, Dibbens Leanne M, Hopper John L, Berkovic Samuel F
Abstract excerpt
OBJECTIVE: Analysis of twins with epilepsy to explore the genetic architecture of specific epilepsies, to evaluate the applicability of the 2010 International League Against Epilepsy (ILAE) organization of epilepsy syndromes, and to integrate molecular genetics with phenotypic analyses. METHODS: A total of 558 twin pairs suspected to have epilepsy were ascertained from twin registries (69%) or referral (31%)....
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