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EGF rs11568835 G/A polymorphism is associated with increased risk of rheumatoid arthritis.

Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals - 1 Nov 2014

Wang Liqun, Bo Lin, Yan Ting, Zhang Hui, Zhou Guoxin, Liu Ruiping

Abstract excerpt

Rheumatoid arthritis (RA) is an autoimmune rheumatological disease thought to have substantial genetic contributions. Epidermal growth factor (EGF) can activate DNA synthesis and cellular proliferation. Early RA synovial fluid was characterized by significantly elevated levels stromal cell and macrophage-related cytokines including EGF. We therefore hypothesized that EGF polymorphisms may contribute to RA...

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PMID: 25089940
DOI: 10.3109/1354750X.2014.946450

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EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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