Article
Association of low-activity MAOA allelic variants with violent crime in incarcerated offenders.
Journal of psychiatric research - 1 Nov 2014
Stetler Dean A, Davis Chad, Leavitt Kathryn, Schriger Ilana, Benson Katie, Bhakta Samir, Wang Lam Chee, Oben Cynthia, Watters Matthew, Haghnegahdar Tara, Bortolato Marco
Abstract excerpt
The main enzyme for serotonin degradation, monoamine oxidase (MAO) A, has recently emerged as a key biological factor in the predisposition to impulsive aggression. Male carriers of low-activity variants of the main functional polymorphism of the MAOA gene (MAOA-uVNTR) have been shown to exhibit a greater proclivity to engage in violent acts. Thus, we hypothesized that low-activity MAOA-uVNTR alleles may be...
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