Article
Hyperlipoproteinemia type 3: the forgotten phenotype.
Current atherosclerosis reports - 1 Sept 2014
Hopkins Paul N, Brinton Eliot A, Nanjee M Nazeem
Abstract excerpt
Hyperlipoproteinemia type 3 (HLP3) is caused by impaired removal of triglyceride-rich lipoproteins (TGRL) leading to accumulation of TGRL remnants with abnormal composition. High levels of these remnants, called β-VLDL, promote lipid deposition in tuberous xanthomas, atherosclerosis, premature coronary artery disease, and early myocardial infarction. Recent genetic and molecular studies suggest more genes than...
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