Article
Cost-effectiveness analysis of sofosbuvir plus peginterferon/ribavirin in the treatment of chronic hepatitis C virus genotype 1 infection.
Alimentary pharmacology & therapeutics - 1 Sept 2014
Saab S, Gordon S C, Park H, Sulkowski M, Ahmed A, Younossi Z
Abstract excerpt
BACKGROUND: Sofosbuvir, an oral NS5B nucleotide polymerase inhibitor, is indicated for the treatment of patients infected with hepatitis C virus (HCV). AIM: To evaluate the long-term health economic outcomes of sofosbuvir + pegylated interferon alfa/ribavirin (pegIFN/RBV) compared with current treatments in patients infected with HCV genotype 1 in the US. METHODS: A decision-analytic Markov model was developed to...
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