Gene-gene interactions and risk of recurrent miscarriages in carriers of endocrine gland-derived vascular endothelial growth factor and prokineticin receptor polymorphisms.

Abstract excerpt

OBJECTIVE: To study endocrine gland-derived vascular endothelial growth factor (EG-VEGF), prokineticin receptor (PROKR) 1, and PROKR2 variants in the coding regions of idiopathic recurrent miscarriage (RM) patients and further evaluate gene-gene interactions of these three genes. DESIGN: Case-control study. SETTING: University-based reproductive clinics and genetics laboratory. PATIENT(S): A total of 142 women...

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