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Article

In silico analysis of miRNA-mediated gene regulation in OCA and OA genes.

Cell biochemistry and biophysics - 1 Dec 2014

Kamaraj Balu, Gopalakrishnan Chandrasekhar, Purohit Rituraj

Abstract excerpt

Albinism is an autosomal recessive genetic disorder due to low secretion of melanin. The oculocutaneous albinism (OCA) and ocular albinism (OA) genes are responsible for melanin production and also act as a potential targets for miRNAs. The role of miRNA is to inhibit the protein synthesis partially or completely by binding with the 3'UTR of the mRNA thus regulating gene expression. In this analysis, we predicted...

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Source

Identifiers

PMID: 25060099
DOI: 10.1007/s12013-014-0152-9

Genes

OCA2
TYR
TYRP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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