Article
Colonic phenotype of the ileum in Crohn's disease: a prospective study before and after ileocolonic resection.
Inflammatory bowel diseases - 1 Sept 2014
Ascolani Marta, Mescoli Claudia, Palmieri Giampiero, Sica Giuseppe, Calabrese Emma, Petruzziello Carmelina, Onali Sara, Albertoni Laura, Lolli Elisabetta, Condino Giovanna, Pallone Francesco, Rugge Massimo, Biancone Livia
Abstract excerpt
BACKGROUND: Colonic metaplasia has been described in pouchitis. In a prospective study, we investigated whether colonic phenotype may develop in Crohn's disease (CD) ileum. The expression of sulfomucins (colonic mucin), sialomucins, and CD10 (small intestine mucin and phenotype) was evaluated before and after ileocolonic resection for CD. METHODS: From February 2007 to March 2010, 22 patients with CD undergoing...
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