Article
Vaccine-associated varicella and rubella infections in severe combined immunodeficiency with isolated CD4 lymphocytopenia and mutations in IL7R detected by tandem whole exome sequencing and chromosomal microarray.
Clinical and experimental immunology - 1 Dec 2014
Bayer D K, Martinez C A, Sorte H S, Forbes L R, Demmler-Harrison G J, Hanson I C, Pearson N M, Noroski L M, Zaki S R, Bellini W J, Leduc M S, Yang Y, Eng C M, Patel A, Rodningen O K, Muzny D M, Gibbs R A, Campbell I M, Shaw C A, Baker M W, Zhang V, Lupski J R, Orange J S, Seeborg F O, Stray-Pedersen A
Abstract excerpt
In areas without newborn screening for severe combined immunodeficiency (SCID), disease-defining infections may lead to diagnosis, and in some cases, may not be identified prior to the first year of life. We describe a female infant who presented with disseminated vaccine-acquired varicella (VZV) and vaccine-acquired rubella infections at 13 months of age. Immunological evaluations demonstrated neutropenia,...
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