Article
Ocular toxicity in BRAF mutant cutaneous melanoma patients treated with vemurafenib.
American journal of ophthalmology - 1 Oct 2014
Choe Christina H, McArthur Grant A, Caro Ivor, Kempen John H, Amaravadi Ravi K
Abstract excerpt
PURPOSE: To determine the frequency of ocular adverse effects associated with vemurafenib (PLX4032) treatment for metastatic cutaneous melanoma. DESIGN: Retrospective review of the clinical study reports from the clinical pharmacology, phase 1, phase 2, and phase 3 trials of vemurafenib. METHODS: The vemurafenib clinical trials were a multicenter series involving adult patients with histologically confirmed,...
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