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Article

Risk for estrogen-dependent diseases in relation to phthalate exposure and polymorphisms of CYP17A1 and estrogen receptor genes.

Environmental science and pollution research international - 1 Dec 2014

Huang Po-Chin, Li Wan-Fen, Liao Pao-Chi, Sun Chien-Wen, Tsai Eing-Mei, Wang Shu-Li

Abstract excerpt

Evidence has shown that polymorphisms of various genes known to be involved in estrogen biosynthesis and function are associated with estrogen-dependent diseases (EDDs). These genes include CYP17A1, estrogen receptor 1 (ESR1), and 2 (ESR2). Phthalates are considered estrogenic endocrine disruptors, and recent research has suggested that they may act as a risk factor for EDDs. However, extremely few studies have...

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Source

Identifiers

PMID: 25030786
DOI: 10.1007/s11356-014-3260-6

Genes

ESR1
ESR2
GSTM1

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