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Article

STING-Associated Vasculopathy with Onset in Infancy — A New Interferonopathy

16 Jul 2014

Abstract excerpt

The past 20 years have seen remarkable progress in our understanding of pathogen recognition by hematopoietic and nonhematopoietic cells. Central to this process is the sensing of microbial components by germline-encoded receptors. In the case of viruses, viral RNA and DNA are chief among the biologic motifs recognized by these receptors.In 2006, it was shown that transfection of DNA into various cell types...

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PMID: 25029336
DOI: 10.1056/nejme1407246

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STING-Associated Vasculopathy with Onset in Infancy — A New InterferonopathyPMID 25029336Read ↗

A rare manifestation of STING-associated vasculopathy with onset in infancy: a case report.Semantic proximity Read ↗

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A Mutation Outside the Dimerization Domain Causing Atypical STING-Associated Vasculopathy With Onset in InfancySemantic proximity Read ↗

A novel STING1 variant causes a recessive form of STING-associated vasculopathy with onset in infancy (SAVI).Semantic proximity Read ↗

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[Stimulator of interferon genes-associated vasculopathy with onset in infancy: first case report in China].Semantic proximity Read ↗

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Expression of a constitutively active humanSTINGmutant in hematopoietic cells produces anIfnar1-dependent vasculopathy in miceSemantic proximity Read ↗

Stimulator of Interferon Genes-Associated Vasculopathy With Onset in Infancy: A Mimic of Childhood Granulomatosis With Polyangiitis.Semantic proximity Read ↗

STING-Associated Vasculopathy with Onset in Infancy in Three Children with New Clinical Aspect and Unsatisfactory Therapeutic Responses to Tofacitinib.Semantic proximity Read ↗

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