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Article

Associations between androgen receptor CAG & GGN repeat polymorphism & recurrent spontaneous abortions in Chinese women.

The Indian journal of medical research - 1 May 2014

Chuan Zhang, Jie Dang, Hao Xu, Junhua Bao, Mengjing Guo, Liguo Pei, Yousheng Yan, Hong Lu, Zhenghao Huo

Abstract excerpt

BACKGROUND & OBJECTIVES: Recurrent spontaneous abortion (RSA) is a reproductive problem that occurs in women in reproductive age with a frequency of 1-3 per cent. Previous studies have reported high levels of serum androgens to be associated with RSAs. At the molecular level, the effect of androgens is mediated through the activation of the androgen receptor (AR). The CAG and GGN repeat polymorphisms of the AR...

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PMID: 25027083
PMCID: PMC4140038

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