Article
Development of a prediction model for lymph node metastasis in luminal A subtype breast cancer: the possibility to omit sentinel lymph node biopsy.
Cancer letters - 10 Oct 2014
Nakauchi Chiaki, Naoi Yasuto, Shimazu Kenzo, Tsunashima Ryo, Nishio Minako, Maruyama Naomi, Shimomura Atsushi, Kagara Naofumi, Shimoda Masashi, Kim Seung Jin, Noguchi Shinzaburo
Abstract excerpt
The present study aimed to construct a prediction model for axillary lymph node metastasis (ALNM) using a DNA microarray assay for gene expression in breast tumor tissues. Luminal A breast cancers, diagnosed by PAM50 testing, were analyzed, and a prediction model (genomic nodal index (GNI)) consisting of 292 probe sets for ALNM was constructed in a training set of patients (n=388), and was validated in the first...
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