Article
A subpathway-based method of drug reposition for polycystic ovary syndrome.
Reproductive sciences (Thousand Oaks, Calif.) - 1 Apr 2015
Liu Hai-Ying, Liu Jian-Qiao, Mai Zi-Xin, Zeng Yan-Ting
Abstract excerpt
The need for development of new therapeutic agents for polycystic ovary syndrome (PCOS) is urgent due to general lack of efficient and specialized drugs currently available. We aimed to explore the metabolic mechanism of PCOS and inferred drug reposition for PCOS by a subpathway-based method. Using the GSE34526 microarray data from the Gene Expression Omnibus database, we first identified the differentially...
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