Article
Genetics and the clinical approach to paragangliomas.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme - 1 Dec 2014
Schulte K-M, Talat N, Galata G, Aylwin S, Izatt L, Eisenhofer G, Barthel A, Bornstein S R
Abstract excerpt
This study analyses new information on gene mutations in paragangliomas and puts them into a clinical context. A suspicion of malignancy is critical to determine the workup and surgical approach in adrenal (A-PGL) and extra-adrenal (E-PGL) paragangliomas (PGLs). Malignancy rates vary with location, family history, and gene tests results. Currently there is no algorithm incorporating the above information for...
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