Article
Claudin-1 is a novel target of miR-375 in non-small-cell lung cancer.
Lung cancer (Amsterdam, Netherlands) - 1 Sept 2014
Yoda Satoshi, Soejima Kenzo, Hamamoto Junko, Yasuda Hiroyuki, Nakayama Sohei, Satomi Ryosuke, Terai Hideki, Ikemura Shinnosuke, Sato Takashi, Naoki Katsuhiko, Betsuyaku Tomoko
Abstract excerpt
OBJECTIVES: We previously reported low expression of miR-375 in squamous-cell carcinoma (SCC) and high expression in adenocarcinoma (AC) of the lung. miR-375's target genes and its function in non-small-cell lung cancer (NSCLC) have not been elucidated. Therefore, the present study was designed to identify the targets of miR-375 and to characterize its function in NSCLC. MATERIALS AND METHODS: Candidate targets...
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