Article
Association study between interleukin-12 receptor β1/β2 genes and allergic rhinitis in the Chinese Han population.
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery - 1 Apr 2015
Wei Ping, Kou Wei, Sun Rong, Hu Guo-Hua, Hu Di, Feng Jing, Hong Su-Ling, Kang Hou-Yong
Abstract excerpt
Interleukin-12 (IL-12) plays a key role in the protection against allergic reaction induced by allergen as well as the differentiation of T helper 1 cells in patients with allergic rhinitis (AR), exerting its biological effects through binding to specific IL-12 receptors (IL-12Rs) termed IL-12Rβ1 and IL-12Rβ2. In this study, we investigated the relationship between polymorphisms in the IL-12R gene and AR in the...
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