Article
HIF1A as a major vascular endothelial growth factor regulator: do its polymorphisms have an association with age-related macular degeneration?
Clinical & experimental ophthalmology - 1 Jan 2000
Okur Volkan, Cetin Ozan, Cetin Ebru, Tepeli Emre, Bulgu Yunus, Yildirim Cem
Abstract excerpt
BACKGROUND: To investigate the association between age-related macular degeneration (AMD) and the polymorphisms of HIF1A, a major vascular epithelial growth factor regulator under hypoxic conditions. The associations of AMD and polymorphisms of genes CFH, SKIV2L and MYRIP were also studied. DESIGN: Prospective study. PARTICIPANTS: Eighty-seven AMD patients and 80 healthy subjects admitted to the Department of...
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