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Article

MiR-15b Targets Cyclin D1 to Regulate Proliferation and Apoptosis in Glioma Cells

1 Jan 2014

Abstract excerpt

AIM: To investigate the role and mechanism of miR-15b in the proliferation and apoptosis of glioma. METHODS: The miR-15b mimics were transfected into human glioma cells to upregulate the miR-15b expression. Cyclin D1 was determined by both western blotting analysis and luciferase reporter assay. Methylthiazol tetrazolium (MTT) and flow cytometry were employed to detect the cell proliferation, cell cycle, and...

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PMID: 24995320
DOI: 10.1155/2014/687826

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